A mixed model framework for teratology studies
نویسندگان
چکیده
منابع مشابه
A mixed model framework for teratology studies.
A mixed model framework is presented to model the characteristic multivariate binary anomaly data as provided in some teratology studies. The key features of the model are the incorporation of covariate effects, a flexible random effects distribution by means of a finite mixture, and the application of copula functions to better account for the relation structure of the anomalies. The framework...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2009
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxp028